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Copyright © 2017 Pearson Education, Inc.

CHAPTER 24

The Organic Chemistry of the Metabolic Pathways

Important Terms

acyl adenylate

R

O

adenosine

O

C

O

O

P

O

acyl phosphate

O

R

O

O

C

O

P

O

acyl pyrophosphate

R

O

O

C

O

P

O

O

O

O

P

O

allosteric activator/inhibitor

a compound that activates/inhibits an enzyme by binding to a site on the enzyme

other than the active site.

anabolism

the reactions living organisms carry out that result in the synthesis of complex

biomolecules from simple precursor molecules.

catabolism

the reactions living organisms carry out to provide energy and simple precursor

molecules for synthesis.

citric acid cycle

a series of reactions that convert the acetyl group of acetyl-CoA into two molecules

of CO

2

and a molecule of CoASH.

fatty acid

a long, straight-chain carboxylic acid.

feedback inhibitor

a compound that inhibits a step at the beginning of the pathway for its biosynthesis.

gluconeogenesis

the synthesis of glucose from pyruvate.

glycolysis

the series of reactions that converts glucose to two molecules of pyruvate.

high-energy bond

a bond that releases a great deal of energy when it is broken.

metabolism

reactions living organisms carry out to obtain the energy they need and to synthesize

the compounds they require.

B

-oxidation

a repeating series of four reactions that convert a fatty acyl-CoA molecule into

molecules of acetyl-CoA.