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Chapter 18 619

Copyright © 2017 Pearson Education, Inc.

e.

Br

O

O

Br

g.

CH

2

CH

3

Br

Br

CH

2

CH

3

+

f.

OH

SO

3

H

OH

SO

3

H

h.

COOH

COOH

49.

The more activating the substituent, the more basic the NH

2

group.

CH

3

O

NH

2

CH

3

NH

2

Br

NH

2

CH

3

C

NH

2

O

>

>

>

50.

The least reactive compound yields the highest percentage of meta product.

N(CH

3

)

3

+

CH

2

N(CH

3

)

3

+

CH

2

CH

2

N(CH

3

)

3

+

least reactive

highest % meta product

most reactive

OCH

2

CH

3

CH

2

OCH

3

COCH

3

least reactive

highest % meta product

most reactive

O

2.

3.

CH

3

CHF

2

CF

3

1.

evitcaertsael

evitcaertsom

highest % meta product